Text Link In the anime, Karin and her mother were allowed to take refuge in Kusagakure, on the condition that her mother healed the village's wounded under watch by Zōsui. After the village suffered many casualties following a surprise attack, her mother upheld her duties and healed the wounded at the Kusagakure hospital, where she died after transferring too much chakra to the wounded. Immediately afterward, the duty was passed onto Karin, much to her disapproval. Sometime after becoming a genin, Karin took part in the Chūnin Exams held in Konoha on a team. During the second phase, Karin lost track of her teammates and was attacked by a large bear. She was saved by Sasuke Uchiha, who was disappointed to find she had an earth scroll as well, but she was able to catch a good glimpse of him, as he smiled at her. Her team later failed as they didn't make it to the tower with both scrolls by the fifth day. Soon after during a war, Karin sensed a huge group of people approaching the village she was staying in and hid while they attacked. After the village was burned down and everyone was killed, she was approached by Orochimaru, who asked her how she survived, leading him to bring her back to Otogakure. During her time with Orochimaru, Karin's healing abilities were studied by Orochimaru and Kabuto, with the latter successfully being able to replicate it. After being involved in experiments with Jūgo and Kimimaro, Orochimaru made her in charge of the Southern Hideout.